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Lee, G., et al., Oxidative dimerization of PHD2 is responsible for its inactivation and contributes to metabolic reprogramming via HIF-1alpha activation

doi: 10.3389/fcell.2023.1226044 22 GaoMYiJZhuJMinikesAMMonianPThompsonCBet al

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Elevated HMOX1 expression leads to increased iron concentrations and high levels of ferrous iron [294], which can accelerate the Fenton reaction when radical scavengers are insufficient [295]

There are mixed opinions on whether intermittent fasting offers unique metabolic or longevity benefits over other structured dieting methods, such as calorie tracking or macro-based eating